SPECIFICITY IN CANCER TREATMENT BASED ON CELL MECHANICS

The presented work is composed of a tight cross-talk between computational modelling and advanced experimental methods, aiming to optimize the design of drug carriers for cancer treatment. Our scheme relays on mechanical differences between normal and tumor cells as were observed in numerous types of cancers; tumor cells were found to be more flexible and deformable compared to normal cells. Preliminary results show that the treatment specificity can be significantly enhanced by using colloids whose engulfment requires massive cell deformation.