The number of patients admitted into Intensive Coronary Care Unit (ICCU) is increasing.
Aim of the study: To analyze the prognosis of the patients who survived OHCA and admitted into ICCU and identify the predictor variables of mortality.
Methods. We retrospectively studied the clinical and prognostic characteristics in survived OHCA consecutive patients admitted into ICCU, from 1-1-2009 to 30-11-2015.
Results: In the study were included 110 patients: 43 patients (39%) died and 67 patients (61%) were discharged alive. The patients who died were older compared with those who survived (64.9±11.7 versus 56.1±13.4 years). The variables associated with a worse prognosis were diabetes mellitus, obesity, asystole as the initial rhythm observed and presence of significant Anoxic Brain Damage (CPC≥3). Ventricular Fibrillation, as the initial rhythm observed, and performance of Emergency Percutaneous Coronary Intervention of the culprit artery were more frequent in the survived patients (Table).
Baseline Characteristics |
Discharged patients N=67 (%) |
Died patients N=43 (%) |
P value |
Age Mean±SD |
56.1±13.4 years |
64.9±11.7 years |
<0.05 |
Diabetes Mellitus |
18 (27) |
25 ( 58) |
<0.05 |
Obesity |
13 (19) |
16 (37) |
<0.03 |
Anoxic Brain Damage |
22 (32) |
33 (76) |
<0.0001 |
LVEF Mean±SD |
39.5±11.3% |
38.6 ±7.7 % |
=0.6 |
Acute Coronary Syndrome |
46 (68) |
24(56) |
=0.3 |
Emergency PCI |
41(61) |
20 (46) |
<0.05 |
Therapeutic Hypothermia |
18 (26) |
12 ( 27) |
=0.9 |
Ventricular Fibrillation |
55 (82) |
16 (37) |
<0.0001 |
Asystole |
12 (17) |
27 (62) |
<0.0001 |
SD=Standard Deviation; LVEF= Left Ventricular Ejection Fraction; PCI= Percutaneous Coronary Intervention
Conclusions: Mortality of patients who survived OHCA and were admitted in ICCU remains high, being post anoxic neurological impairment its main cause.