Cardiogenic Shock Complicating Acute Myocardial Infarction: are there any Gender Differences?

Background and Objectives: Cardiogenic shock (CS) complicating acute myocardial infarction (AMI) is associated with high mortality. Previous studies regarding gender-specific differences in CS revealed conflicting results. The aim of this study was to assess the impact of gender on mortality in patients with CS complicating AMI.

Methods: We analyzed 194 consecutive patients presenting with CS and AMI and who underwent primary PCI in Rabin Medical Center. We compared the demographic and angiographic characteristics of each gender and the effects of gender on clinical outcomes.

Results: After multivariable adjustment, renal failure [OR=1.8, 95%CI=1.4-2.3, P=0.001] and DM [OR=2.3, 95%CI=1.1-4.9, P=0.03] were found to be statistically significant predictors of one month mortality while gender was no longer statistically significant [OR=1.4, 95%CI=0.6-3, P=0.4]

Conclusions: Women with CS complicating AMI had a worse-risk profile in comparison to men. No significant gender-related differences in one month mortality were observed.