We have upgraded wound therapy by the simultaneous administration of irrigation & supplemental oxygen as Regulated Oxygen-Enriched & Irrigation Negative Pressure-Assisted Wound Therapy (ROI-NPT), to synergistically combat wound infection. Irrigation may accelerate evacuation of infectious material from the wound. We maintain that ROI-NPT will provide a global platform technology for wound healing systems as well as an affordable, cost-effective alternative method to hyperbaric oxygen treatment (HBO). The TopClosure® Tension Relief System (TRS) is a novel device for wound stretching, closure and secure, applying stress relaxation and mechanical creep for primary closure of large skin defects which otherwise would have required closure by skin grafts, flaps or tissue expanders.
The combination of TRS and ROI-NPT alters the three phases of wound healing by reducing inflammation, eliminating the need for lengthy proliferation of granulation tissue and enabling improved functionality. This unique synergistic effect provides a totally new concept of wound management that changes perceptions of wound closure, instituting new standards of care for optimizing wound healing.