One-step sonochemical synthesis of carbon dots (C-dots), which is carried out by sonication of pristine polyethylene glycol (PEG-400) for 0.5-3 hour. It demonstrates how various experimental parameters, such as the sonication time, the temperature and the amplitude of sonication affect the size of the C-dots (2-10 nm) and their fluorescence. The highest measured quantum yield of emission was ~16-44%. Similarly, we synthesized C-dots doped with metals (Ga, In, Sn) and non-metals (N, P, S) for various applications, such as supercapacitor, Lithium ion rechargeable battery, biodiesel production, bio-imaging, antibacterial activity, Neural cell growth, and gene delivery. The synthesized C-dots were coated on polythene, Si-wafer and activated carbon (AC). C-dots were used for bio-imaging, whereas AC/C-dots were used as supercapacitors. Electrodes made of AC/C-dots demonstrated specific capacitance of 0.185 F.g-1.cm-2, almost 3 times higher than unmodified carbon. The Sn@C-dots@Sn nanoparticles were synthesized and directly deposited on the copper foil current collector as a promising anode for Li-ion batteries. The letter, C-dots modified SrO NPs was prepared from the Sr-based salt (Sr(NO3)2) and to study their physical, chemical and catalytic behavior. This catalyst (SrO-C dot composite) is very useful as a catalyst for biodiesel production from the cooked waste oil and Chlorella vulgaris microalgae. Similarly, TiO2 materials was synthesized and used for photocatalytic activity. The Ga doped in C-dots (Ga@C-dots) and used for antimicrobial activity against free-living P. aeruginosa bacteria. Ga@C-dots was reflected full inhibition of the bacterial growth at the much lower concentration of Ga within Ga@C-dots. We also observed that cells grown on a Ga@C-dots@Ga-coated substrate exhibit a 96% increase in the number of branches originating from the soma (SH-SY5Y cells).