Unidentified Renal Dysfunction among Patients Undergoing Trans-Catheter Aortic Valve Implantation - The 64th Annual Conference of the Israel Heart Society & The Israel Society of Cardiothoracic Surgery, 25-26 April 2017

Zach Rozenbaum ^1,4 David Pereg ^2,4 Asta Balchyunayte ³ Jeremy Ben Shoshan ^1,4 Shmuel Banai ^1,4 Ariel Finkelstein ^1,4

¹Cardiology, Sourasky Medical Center
²Cardiology, Meir Medical Center
³Internal Medicine D, Sourasky Medical Center
⁴Sackler Medical School, Tel Aviv University

Introduction:
Renal dysfunction is known as a predictor of adverse outcomes in patients undergoing trans-catheter aortic valve implantation (TAVI). The prevalence and clinical significance of patients with impaired renal function but with a normal serum creatinine among patients undergoing TAVI have not been studied to date.

Methods:
The cohort included 1527 TAVI patients from 3 tertiary medical centres. Pre-procedural serum creatinine concentration was noted, and estimated glomerular filtration rate (eGFR) was calculated according to the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), the Modification of Diet in Renal Disease Study (MDRD) and the Cockroft-Gault formulas. Unidentified renal dysfunction was defined as a serum creatinine <1.2mg/dl and eGFR

Results:
Almost a forth (23.2%) of the patients had a serum creatinine<1.2mg/dl and an eGFR

Conclusion:
TAVI patients with unidentified renal dysfunction should be considered as a high risk population. A different therapeutic approach in these patients should be evaluated.