The efficacy of the Icon application in improving adherence to treatment with stimulant medications in children with ADHD

Psychostimulants are considered effective treatment for ADHD. Still, the rates of adherence to stimulants are low in children and adolescents diagnosed with the disorder. Smartphone applications (i.e., mobile apps) are suggested as effective tools for the promotion of healthcare delivery, including medication adherence. However, to the best of our knowledge, no study has yet to examine the utility of a mobile app for promoting medication adherence in youth with ADHD. In this lecture, we will present preliminary findings from a study recently completed at Sheba Medical Center. The study sample included 39 children (27 males), aged 9.56 ± 2.41 years, who met criteria for a diagnosis of ADHD according to the DSM-5. Children were divided into study group (i.e., were prompted to use the Icon app) and control group (i.e., treated as usual, without the Icon app). The groups were matched for age, and sex distribution and were followed for 8 weeks. Major outcome measures included pill-count and the Clinician Rating Scale (CRS) score at 4 and 8-weeks post enrollment to the study. Preliminary findings suggest a statistically significant improvement in total CRS score in the study group vs. the control group. In addition, pill-count increased significantly in the study group as compared with controls, providing initial support for the utility of the Icon app (and the associated intervention model) for increasing adherence to stimulants intake among youth with ADHD.