Situation of Iodine Deficiency in the Tomsk Region, Russia in 15 Years

The aim of this study is a comparative analysis of the epidemiological situation of iodine deficiency in the Tomsk region from 1998 to 2014 year. 9901 and 15174 school-age children were surveyed in the city of Tomsk. Medical history, anthropometric measurements were analyzed for all students, thyroid ultrasonography was performed with portable scanner “Aloka SSD 500” with linear transducer frequency of 7.5 MGz. The excretion of inorganic iodine in urine was determined at 264 children in 1998 year and 120 children in 2014 year respectively, in a single urine portion using cerium-arsenit method. Analysis of TSH results was done to 10717 newborns in 1998, аnd to 15091 newborns in 2014 in capillary blood samples taking on 4 - 5 days after birth. Neonatal TSH were determined by fluorometric immunoassay kits using TSH-Neonatal: Delfia, Finland. According to our survey median urinary iodine of schoolchildren was 72.5 mcg/l in 1998, and 92 mcg/l in 2014, which shows both the increase in iodine provision of the population over 15 years on 27%, and keeping the level of urinary iodine, wich corresponds to mild iodine deficiency according to WHO criteria. Increase of level of TSH>5MU/l was registered in 11,7% of newborns in 1998 and in 7.7% of newborns in 2014, which shows the mild degree of iodine deficiency. Comparative analysis of the epidemiological situation of iodine deficiency in Tomsk for 1998 and 2014 shows iodine provision growth on 27% over 15 years, also the decrease in frequency of neonatal hyperthyrotropinemia in 1.5 times, but all criteria stacked indicate mild degree of iodine deficiency in Tomsk region.