The Relationship between Non Fasting Triglyceride with Severity of Coronary Artery Disease

Background: Cardiovascular disease is a major cause of death in both men and women around the world. Studies have shown that more hypertriglyceridemia is an important risk factor of cardiovascular disease. While triglyceride levels after a meal increase, relationship between postprandial triglyceride levels and severity of coronary artery disease is still unproven.
This study aimed to determine plasma levels of triglyceride after a meal in patients with different types of coronary heart disease.
Methods: In this epidemiological analysis study, 416 patients among those referred to Golestan Hospital in Ahvaz were selected based on the results of angiography and were classified to type 1 to 4 groups including 69, 99, 83 and 165 individuals respectively, and their age and sex were recorded. From all individuals, a blood sample was taken 2 hours after a meal. Data were analyzed using Tukey test.
Results: The mean age of patients was 58.4 years. There was only significant difference between the groups with type 1 (142±67.1 mg/dL) that were normal and type 4 (188±99.3 mg/dL) with severe coronary artery disease (p<0.001). Furthermore, no significant difference between the mean triglyceride levels was observed in both sexes in different types (p>0.05).
Conclusions: Results showed that triglyceride serum level after a meal in patients with severe coronary artery disease (type 4) is higher than the other groups and hypertriglyceridemia after a meal may be a major factor in coronary heart disease.
Keywords: Triglyceride, non-fasting, coronary artery disease, angiography.