Long-Term Follow-Up of Patients with Severe Aortic Stenosis Treated with a Self-Expanding Prosthesis - ICCAD 2017 - The 12th International Congress on Innovations in Coronary Artery Disease , 15-17 October, 2017 Venice, Italy

Pablo Avanzas ^1,4 Isaac Pascual ^1,4 Antonio Muñoz ² José Segura ³ Juan Horacio Alonso-Briales ² Javier Suárez de Lezo ³ Manuel Pan ³ Manuel Jiménez-Navarro ² José López-Aguilera ³ José María Hernández-García ² César Moris ^1,4

¹Area del Corazón, Hospital Universitario Central de Asturias
²Servicio de Cardiología, Hospital Clínico Universitario Virgen de la Victoria
³Servicio de Cardiología, Hospital Universitario Reina Sofía
⁴Area del Corazón, Instituto de Investigación Sanitaria del Principado de Asturias

Introduction and objectives: Transcatheter aortic valve implantation (TAVI) is a safe and effective alternative to surgical treatment in patients with severe aortic stenosis (AS) and those who are inoperable or at high surgical risk. The primary objective of this study was to evaluate the long-term survival of consecutive patients with severe AS treated with TAVI.
Material and methods: Observational, multicenter, prospective, follow-up study of consecutive patients with severe symptomatic AS treated by TAVI in 3 high-volume hospitals in Spain.
Results: We recruited 108 patients, treated with a self-expanding CoreValve prosthesis. The mean age at implantation was 78.6 ± 6.7 years, 49 (45.4%) were male and the mean logistic EuroSCORE was 16% ± 13.9%. The median follow-up was 6.1 years (2232 days). Survival rates at the end of years 1, 2, 3, 4, 5, and 6 were 84.3% (92.6% after hospitalization), 77.8%, 72.2%, 66.7%, 58.3%, and 52.8%. During follow-up, 71 patients (65.7%) died, 18 (25.3%) due to cardiac causes. Most (82.5%) survivors were in New York Heart Association class I or II. Six patients (5.5%) developed prosthetic valve dysfunction.
Conclusions: Long-term survival in AS patients after TAVI is acceptable. The main causes of death are cardiovascular in the first year and noncardiac causes in subsequent years. Valve function is maintained over time.