Remote Photonic Sensing of Hemodynimics of Brain Activity

In this paper a unique and novel method for remote brain activity monitoring is presented. A new theoretical foundation and an experimental understanding of the underlying technologies in all phases of the project will be developed. The presented approach includes observation of the secondary speckle patterns that are created by illuminating the skull using a laser beam. Nano vibrations due to blood flow and tissue oxygenation of the brain cause the self-interference random patterns to change as the interference affects the light waves. By using this approach, the temporal nanometric change of the speckle pattern due to hemodynamic response can be tracked. The simple device consists of a laser and a camera. Using the presented method, one can illuminate several spatial points simultaneously with a laser and detect the temporal and spatial effects with a camera. The primary objective of this project is to use remote sensing of brain blood flow changes approaches to establish a new type of a superior, low cost, remote and optical device having nanometric resolution for remote sensing of brain activity for clinical use.