Introduction:
We report a 12 days old infant who was admitted to our Hospital with Proteus mirabilis meningitis and had been successfully treated with Carbapenem and recovered with no neurological damage in contrast to other cases of p. meningitis that been reported in literature and we reviewed.
P.mirabilis, a Gram negative bacteria which most frequently leading for urinary tract infections and causes about 4% of neonatal sepsis and may produce AmpC extended spectrum β lactamase.
Case report:
A previously healthy infant boy 12 days old was admitted to our hospital because of fever, without any other symptoms.
His past medical history was remarkable for a circumcision five days prior to his admission.
Due to his age, a full sepsis workup been taken; on second day for the admission the CSF culture revealed a growth of P. mirabilis. No growth was reported from urine and blood cultures. After consultation with infectious disease specialists, and based on possibility of AmpC β lactamase production, the antibiotic therapy was changed to IV Meropenem which was given for 3 weeks.
Under the treatment, the baby was well with no pathology.
We repeated the LP after 72 hours under treatment that showed full eradication of the bacteria.
Conclusion:
In most cases been described, p. meningitis appears to be complicated despite the antibiotic treatment, and carry a poor prognosis.
The treatment with Meropenem should be in main due to the increase resistance of the bacteria to beta lactam antibiotics and third generation cephalosporin`s.
