Predictors of Postoperative Complications and Discordance between Surgical Vs. Pathological Diagnosis in Pediatric Complicated Appendicitis

author.DisplayName 1,5 author.DisplayName 4,5 author.DisplayName 2,3,5 author.DisplayName 5 author.DisplayName 4,5 author.DisplayName 2,3,5
1Department of Pediatrics B, Schneider Children's Medical Center of Israel, Petach Tikva, Israel
2Department of Pediatrics A, Schneider Children's Medical Center of Israel, Petach Tikva, Israel
3Unit of Pediatric Infectious Diseases, Schneider Children's Medical Center of Israel, Petach Tikva, Israel
4Department of Pediatric Surgery, Schneider Children's Medical Center of Israel, Petach Tikva, Israel
5Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Introduction: Acute appendicitis is the most common emergency condition in pediatric surgery. Complicated appendicitis, classified as gangrene or perforated, creates a high burden for pediatrics health care system.

Aim: To identify predictors as recorded at admission for postoperative complications following complicated appendicitis in pediatric population.

Methods: Epidemiological, clinical and laboratory data were retrospectively collected for cases defined pathologically as complicated appendicitis between 2012-2015 at Schneider Children`s Medical Center. Potential correlation between these factors and morbidity, length of hospital duration and complications were tested.

Results: Two independent predictors for longer hospital duration were found on multivariate analysis. Longer duration of fever prior to admission (OR 1.815; 95% CI 1.074-3.067, P=0.26) and CRP levels >10 mg/dL (OR 20.494; 95% CI 1.775-236.607, P=0.016). A discrepancy between the surgical and the pathological report was found in 11.7% of cases, all of which were classified intra-operatively as gangrenous. This group demonstrated lower rates of postoperative complications, shorter duration of hospital stay without readmissions.

Conclusions: prolonged hospital stay of pediatric complicated appendicitis may be predicted by the above mentioned preoperative risk factors, that may help define high-risk subgroup of children who will likely benefit from early detection. The operative diagnosis may better predict outcomes, suggesting treating operative finding of gangrenous as with acute simple appendicitis protocols.

Nadav Mizrahi
Nadav Mizrahi








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