Blood Troponin Levels in Acute Cardiac Events Depends by Space Wether Activity Components (A Correlative Study) - The 65th Annual Conference of the Israel Heart Society & The Israel Society of Cardiothoracic Surgery, 24-25 April 2018

Eliyahu Stoupel Division of Cardiology, Rabin Medical Center, Israel Sackler Faculty of Medicine, Tel Aviv University, Israel Richardas Radishauskas Institute of Cardiology, Medical Academy, Israel Lithuanian University of Medical Sciences, Kaunas, Lithuania Gailute Bernotiene Institute of Cardiology, Medical Academy, Israel Lithuanian University of Medical Sciences, Kaunas, Lithuania Abdonas Tamoshiunas Institute of Cardiology, Medical Academy, Israel Lithuanian University of Medical Sciences, Kaunas, Lithuania Dalia Virvichiute Institute of Cardiology, Medical Academy, Israel Lithuanian University of Medical Sciences, Kaunas, Lithuania

Abstract: Many biological processes are influences by Space Weather Activity components- Solar (SA), Geomagnetic (GMA), Cosmic Ray (CRA) activity. Between them can be mentioned Total Mortality, Acute Myocardial Infarction (AMI), Stroke (CVA), Sudden Cardiac Death (SCD), some congenital maladies (Congenital Heart Disease, Down Syndrome), many events in Neonatology, Ophthalmology, Blood Pressure regulation, blood coagulation, inflammation etc.

The aim of this study is to check if the level of blood Troponins- a marker of myocardial damage and a recognized component of modern description of AMI is connected with the mentioned Space Weather parameters.

Methods and patients: Patients admitted to a 3000 beds tertiary University hospital in Kaunas, Lithuania with suspected AMI were the object of the study. Data for years 208-2013 was studied-72 consecutive months. 1896 of the patients (1398 male, 498 female) had a Troponin I (Tp I), or Troponin T ( Tp T, sernsitive Troponin) blood test. Normal values were 0.00-0.03- ng/ml for Tn I and 0.00-014.00 ng/ml for TnT. Monthly means and StD of Tp I and Tp T were compared with monthly markers of SA, GMA, CRA. Pearson correlation coefficients and they probabilities were established (in addition to consecutive graphs of both compared physical and biological data). The cosmophysical data came from Space Service Institutions in the U.S., Russia, Finland.

Results: AMI was diagnosed in 1188 patients (62.66%), Intermediate Coronary Syndrome (ICS) in 698 (36.81%). It were significant links of the Tp blood levels with 4 SA indices, and CRA (Neutron activity in imp/min.) ; No significant correlation with GMA indices Ap., Cp. (p=0.27 and p=0.235).

Conclusion:

1. The monthly level of blood Tp I, T in ACS, is significantly correlated with indices of Solar and (inverse) with Cosmic Ray (Neutron) activity

2. No significant correlation with Geomagnetic Activity indices.

3. Tp. T was significantly correlated with GMA indices A,C, like blood coagulation and inflammation markers