Pediatric Kidney Transplantation Program at Rambam Health Care Campus- Summary of the First Four Years` Experience

Ran Steinberg 1 israel Eisenstein 2 shirly Pollack 2 amir Hadash 3 joseff Ben-Ari 3 anat Ilivitzki 4 Rawi Ramadan 5 Amit Lehavi 6 Ahamed Assalia 8 Aharon Hoffman 7 Daniella Magen 2
1pediatric surgery, Ruth Rappaport Children's Hospital
2PEDIATRIC NEPHROLOGY, Ruth Rappaport Children's Hospital
3Pediatric Intensive care, Ruth Rappaport Children's Hospital
4Radiology Unit, Ruth Rappaport Children's Hospital
5Adult kidney Transplantation Unit, Rambam Health Care Campus and Faculty of Medicine, Technion Institute of Technology, Haifa, Israel
6Pediatric Anesthesiology, Rambam Health Care Campus and Faculty of Medicine, Technion Institute of Technology, Haifa, Israel
7Department of Vascular Surgery, Rambam Health Care Campus and Faculty of Medicine, Technion Institute of Technology, Haifa, Israel
8Division of Advanced Laparoscopic Surgery, Rambam Health Care Campus and Faculty of Medicine, Technion Institute of Technology, Haifa, Israel

Background: Kidney transplantation (KTx) in the pediatric age group requires a multidisciplinary highly skilled and dedicated team, with an appropriate setting. As of 2014 we have launched our Rambam-pediatric KTx program for the north of Israel.

Methods: Demographic and clinical data on all pediatric KTx performed at Rambam between January 2014 and October 2017 was recorded.

Results: A total of 32 pediatric KTx was performed in 12 females and 20 males residing in the north of Israel and in the Palestinian authority, averagely aged 11.6 years (range 2-23). 18 KTx were from living donors, and 14 from cadaveric donors. The main etiologies: renal dysplasia (10), cystic kidney diseases (5) and focal segmental glomerulosclerosis (FSGS) (4). Two patients (6.7%) displayed delayed graft function, four (13.3%) exhibited reversible acute rejection, and one FSGS patient developed early disease recurrence. One patient with additional co-morbidities died after graft loss due to rejection, and an additional patient developed chronic allograft nephropathy. There was no incidence of graft primary non-function. Currently, all other 28 recipients (93.3%) have normal renal function.

Discussion: our short and medium-term results are excellent, and comparable to published data from well-established pediatric KTx programs.

Summary: The volume of pediatric KTx in Israel justifies two pediatric kidney transplantation centers, for the benefit of the northern Israeli population.

Ran Steinberg
Ran Steinberg








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