Engineering at the Nano-Bio Interface

Faithful devotion to Moore’s Law over several decades has led to the scaling of transistor features in commercial products to around 10 nanometers (and soon below) – about the size of many proteins and other biomolecules. This has created new opportunities where the tools of semiconductor manufacturing can be used to address questions in biology and medicine, and, conversely, where biomolecules may play a role in a future nanoelectronics technology. New strategies that combine precision nanofabrication with the exquisite selectivity of biomolecular interactions are broadly applicable and may lead to the development of complex new nanoarchitectures that exploit the best properties of natural and engineered systems toward the emergence of novel phenomena and new capabilities.