Abstract
Photoacoustic and acousto-optic tomography combine light and sound to enable optical-contrast imaging deep inside complex scattering samples, with a depth to resolution ratio beyond the reach of all-optical techniques.
In my talk I will describe the fundamentals of photoacoustic and acousto-optic tomography, and will describe the recent advancements in the fields, which include using the photoacoustic effect as a ‘guide-star’ for optical focusing deep inside scattering media [1], the use of random speckle fluctuations [2-4], compressed-sensing [5-6], and flow-induced effects [7-9] for super-resolution photoacoustic/acousto-optic imaging beyond the acoustical diffraction limit, as well as several other novel advancements in the field.
References
- R. Horstmeyer, H. Ruan, and C. Yang, "Guidestar-assisted wavefront-shaping methods for focusing light into biological tissue," Nature photonics 9, 563-571 (2015).
- B. Judkewitz, Y.M. Wang, R. Horstmeyer, A. Mathy, C. Yang, "Speckle-scale focusing in the diffusive regime with time-reversal of variance-encoded light (TROVE)", Nature Photonics 7 (4), 300-305 (2013)
- T. Chaigne, J. Gateau, M. Allain, O. Katz, S. Gigan, A. Sentenac, and E. Bossy, "Super-resolution photoacoustic fluctuation imaging with multiple speckle illumination," Optica 3, 54-57 (2016).
- D. Doktofsky, M. Rosenberg, O.Katz "Acousto-optic tomography beyond the acoustic diffraction-limit using speckle decorrelation", arXiv:1812.00400 (2018).
- E. Hojman, T. Chaigne, O. Solomon, S. Gigan, E. Bossy, Y. C. Eldar, and O. Katz, "Photoacoustic imaging beyond the acoustic diffraction-limit with dynamic speckle illumination and sparse joint support recovery," Optics Express 25, 4875-4886 (2017).
- T. W. Murray, M. Haltmeier, T. Berer, E. Leiss-Holzinger, and P. Burgholzer, "Super-resolution photoacoustic microscopy using blind structured illumination," Optica 4, 17-22 (2017).
- T. Chaigne, B. Arnal, S. Vilov, E. Bossy, and O. Katz, "Super-resolution photoacoustic imaging via flow-induced absorption fluctuations," Optica 4, 1397-1404 (2017).
- S. Vilov, B. Arnal, and E. Bossy, "Overcoming the acoustic diffraction limit in photoacoustic imaging by the localization of flowing absorbers," Optics letters 42, 4379-4382 (2017).
- X. L. Dean-Ben and D. Razansky, "Localization optoacoustic tomography," Light: Science & Applications 7, 18004 (2018).