Invited
From lab to production: Introduction to process-way-of-thinking in industrial organic chemistry, via case study of a three-step telescoping (domino) type process.

The implementation of an organic reaction on industrial scale requires not only the adjustment of scale, but not less importantly a different way of looking at it.

In addition to focusing on the reaction parameters, focusing on the process is essential.

This add the process-way-of-thinking to the scope of the industrial chemist.

In this talk a process-way-of-thinking will be presented via a case study containing:

1. New chemistry (to the best of our knowledge) for synthesis of organic compound containing sulfur.^[1]
2. Implementation of this chemistry in a scalable manner.
3. Some industrial considerations required upon scale up.
4. Application of the above in a telescoping (domino) type process.

^[1] PCT/US2018/060659