Prevalence & Natural History of Tricuspid Insufficiency in Ischemic Mitral Regurgitation

Background: By clinical observation we noticed that Ischemic Mitral Regurgitation (IMR) may be followed by fTR. A little is known on the prevalence and natural history of patients with both IMR and fTR.

Method: We conducted a retrospective cohort study based on data from January 2012 to December 2014 in EMEK Medical Center. Patients were eligible for the study if they diagnosed with IMR according to known definitions. Mean follow up was five years.

Results: 168 patients developed IMR. In 134 pts, echocardiograms were performed both during admission they formed the study group. Forty pts (30.1%) developed _fTR. These patients were older (63.0 ± 10.4 and 57.1 ± 11.0, respectively, p <0.05) and were previously diagnosed with vascular disease, Coronary (p <.006) or Peripheral (p <.009). Successful PCI was a positive predictor of non-development of TR (p <.003). There was no difference between STEMI and non-STEMI, and nor infarct territory. From an echocardiographic point of view, severity of IMR and mean Pulmonary pressure significantly and directly affected the development of fTR (p

Conclusion: Our study indicates that patients who develop IMR had a 30% risk to developed _fTR during acute phase and additional 16% in the first years. MR Severity is directly proportional to deterioration rate of the TV regardless of pulmonary pressure or right ventricular function. fTR tends to deteriorate in about 20% of patients and it mainly affected by the left ventricular systolic function.