How do we Train Clinicians to Integrate Genomics into Paediatrics?

Background: Approximately 1 in 17 people is affected by a rare disease in the UK, many of which are genetic in origin. Using DNA sequencing, these and many other conditions will soon be diagnosed antenatally or early in life, having major implications on paediatrics in terms of diagnosis, treatment, and prognosis. Many European governments are investing in Genomic Medicine and paediatricians are well placed to recognise these new opportunities and integrate them into their practice.

Objective: In 2017 the Welsh Government introduced the Genomics for Precision Medicine Strategy, aimed at developing genetics and genomics to improve health and healthcare provision in Wales. To help fulfil this strategy, Swansea University launched an MSc in Genomic Medicine in May 2018, the first University in Wales to provide this opportunity to multi-disciplinary health care professionals, imparting the skills and knowledge necessary to interpret genomic data and understand its impact on patient care.

Methods: Based on the indicative curriculum of Health Education England and Genomics England, this 2 year part-time Masters course integrates lectures, workshops, tutorials, interactive group learning and guest lectures, while encouraging and facilitating workplace learning. Modules include bioinformatics, genomics of common and rare inherited diseases, ethics, techniques and optional modules such as pharmacogenomics. Module assessments are summative and students must complete a dissertation describing an applied genomics project, research, or literature review.

Results: Eight students completed their first year of study in January 2019. A variety of healthcare professionals enrolled (e.g. laboratory-based microbiologists, geneticists, pathologists, oncologists and paediatricians) which fostered collaborative work and learning. The formal and informal feedback to all modules has been excellent, with students ranking all aspects as “highly satisfactory”.

Conclusion: The MSc in Genomic Medicine plays a vital role in educating healthcare professionals seeking knowledge and skills in this emerging discipline.