Neonatal Sepsis and Meningitis Caused by Neisseria Oralis: A Case Report

Case:

Female infant was born by Emergency Caesarian Section for Foetal distress at gestational age of 38+4 weeks with a birth weight of 2250 g. The delivery was complicated by prolonged rupture of membranes and foul smelling liquor. She was born in poor condition requiring resuscitation .She was admitted to Neonatal unit for IV antibiotics. Her Initial CRP on admission was raised at 46 with a further increase in CRP to 97 on day 2 of life. Her blood culture and CSF culture grew Neisseraia Oralis , sensitive to Cefotaxime. She was treated with IV cefotaxime for 3 weeks. Her infection markers normalised on Day 6 of life. No major morbidity identified at discharge.

Laboratory Investigations:

Discussion:

Neisseria Oralis are usually harmless inhabitants of otherwise asymptomatic persons` upper respiratory mucosal surfaces. There have been 7 Serotypes of Nesseria Orlis identified from Healthy Oral mucosa^. Recently this commensal has been evolving into a pathogen. There has been a previous case report of N.Oralis Cystitis in a Diabetic Patient.^. Further studies are needed to identify the risk factors that leeds to changes in physiology for these harmless inhabitants to become Pathogens.