A Case of Aplasia Cutis Congenita following Fetal Reduction of Triplet Pregnancy through in vitro Fertilization

Aplasia cutis congenital, defined as absence of all skin layers at birth, results from disrupted development or degeneration of skin in utero, which was first described by Cordon in 1767. In 1986, Frieden classified this congenital skin defect into nine groups based on the distribution of the affected area, associated anomalies, and the mode of inheritance. Fetus papyraceus formed by mummification of dead fetus usually occurs intrauterine death of one co-twin druiing the late first to early second trimesters, whreas earlier or later death of a co-twin typically leads to complete resorption or maceration, respectively.
We report a neonate with bilateral symmetrical ACC on the lower extremities and truncal area with fetus paraceus who was born of a triplet pregnancy that had been artificially reduced to twins which were conceived through in vitro fertilization. We make attention to symmetric truncal ACC as a consequence of the developed fancy reproductive medicine.