Analytical validation of a blood-based test for the earlier detection of multiple cancers

Addressing the unmet medical need of expanding the number cancers that can be detected earlier represents an extraordinary opportunity to reduce cancer deaths. Here, we describe the analytical validation of a noninvasive, blood-based test designed to detect multiple cancers. The test assesses circulating tumor DNA and abnormal protein expression commonly associated with cancer. High analytical performance of the multi-analyte test is demonstrated in clinical and control samples. Practical considerations for future applications of the test in a screening setting will be discussed.