In this roundtable we will present the concept of 3D printing of tissues for regenerative medicine. We will start by a short introduction on the history of 3D bioprinting and the basics of this concept, explaining the need for the technology and describing its impact on modern industry, medical practice and academic research. We will then discuss the different printing approaches, including extrusion, inkjet and laser-assisted technologies. The strengths and limitations of the different technologies will be described, with a focus on the capacity of each method to support fabrication of specific biological structures. We will then try to envision the future of regenerative medicine and the role of advanced fabrication techniques, like 3D printing, in shaping the next generations of this field. Finally, we will discuss latest advances and prominent recent research in the field, give an academic and industry’s perspective, and state the existing challenges in bringing these technologies to the clinic.