Enhanced Ultrasound Imaging using Acoustical Beam Shaping

Background: Ultrasound is a safe, noninvasive, real time and cost-effective clinical imaging modality that can be used to image tissue deep within the body. However, similarly to optics, the resulting performance is restricted by limitations in resolution, contrast and field of view.

Methods: We developed a method to manipulate the emitted acoustical field using an optically-inspired holographic algorithm and then used this as tool to enhance ultrasound imaging capabilities beyond what was feasible in the past.

Results: Beam shaping ultrasound was shown to improve image quality by enhancing resolution, contrast and field of view, as compared to standard ultrasound imaging. Super resolution was achieved by developing acoustical structured illumination; contrast enhancement was achieved by effectively reducing the side lobes using a stimulated emission depletion microscopy inspired method; the field of view was enhanced by superimposing multiple axial multifoci waveforms in a single acoustical transmission.

Conclusion: Optically-inspired beam shaping ultrasound can significantly enhance the performance of ultrasound imaging. These methods can be implemented with conventional ultrasound systems, without the need for additional components, which facilitates their translation into the clinic.