Right ventricular apex (RVA) pacing may have deleterious effects on left ventricular (LV) systolic function. Aim: evaluate the effects of RVA pacing and LV pacing on LV filling velocities. Methods: 54 patients had transthoracic Doppler echocardiographic studies and evaluation of LV diastolic function before and after implantation of a permanent pacemaker. Nineteen patients had LV pacing, 35 had RVA pacing of whom 27 DDD and 8 VVI pacing modes. Results: Before pacing peak E wave velocity averaged 86±34, peak A wave velocity 80±29, ED-deceleration time 192±62msec, annular e velocity 5.5±0.9cm/sec and left atrial diameter 4.4±0.9cm, while after pacing 93±35 cm/sec, 81±30 cm/sec, 175±61cm/sec, 4.5±3cm/sec and 4.3±1cm, respectively, p=ns for all. No significant difference in the measured parameters was found between the different pacing modes, neither before nor after pacing. Conclusions: Pacing mode did not affect LV filling velocity parameters.