ניירות אורז ככלי לאבחן הזעת יתר בכפות אל מול בדיקת יוד-עמילן – מחקר פרוספקטיבי

BACKGROUND: Palmar hyperhidrosis is a common chronic and stigmatizing disease. Accurate diagnosis and assessment of disease severity and response to treatment are crucial for treatment planning and follow up. Currently, the gold standard diagnostic test is the iodine starch test (IST), an inconvenient and poorly reliable method.

AIM: We sought to evaluate the clinical effectiveness and safety profile of a novel approach using moisture response films (MRF) for the detection of primary palmar hyperhidrosis as compared to the standard IST.

METHODS: We performed a prospective comparative study of the 2 tests in 15 patients with primary palmar hyperhidrosis. The severity of the disease was evaluated during 4 sessions (before and after botulinum toxin (BTX) injections), on different days and by different investigators, using the IST and the MRF methods. The physician’s global assessment (PGA) scorings of the results (IST vs. MRF) were evaluated by two independent dermatologists. In addition, the Hyperhidrosis Disease Severity Scale (HDSS) scorings, assessed by the patients at baseline and after BTX injections, were correlated to the IST vs. MRF results

RESULTS: While the objective PGA scoring of the IST results demonstrated poor correlation, the objective PGA scoring of MRF results revealed strong correlation with the patients’ scored HDSS.

CONCLUSION: Analyzing palmar hyperhidrosis with MRFs was found to be superior to the standard IST. It is more efficient, convenient and accurate, and may be considered a better test for the diagnosis of palmar hyperhidrosis.