Health Status of Children and their Parents from Families of Radiation Risk - EAP 2021 Virtual Congress and MasterCourse

Anna Solomakha ¹ Elena Ivanina ² Zoya Nesterenko ¹ Valeria Novikova ^1,2 Margarita Gurova ^1,2 Natalia Prokopyeva ²

¹Department of propaedeutics of children's diseases with a course of General child care, Federal State budgetary Educational Institution of Higher Education «St.Petersburg State Pediatric Medical University» of the Ministry of Healthcare of the Russian Federation, Saint Petersburg, Russia
²Laboratory of medical and social problems in pediatrics, Research Center, Federal State budgetary Educational Institution of Higher Education «St.Petersburg State Pediatric Medical University» of the Ministry of Healthcare of the Russian Federation, Saint Petersburg, Russia

Background: The study of medico-biological aspects of the radiation consequences of the Chernobyl disaster after more than 30 years in families of radiation risk acquires special significance in the analysis of long-term mediated effect of radiation, that performs an important evolutionary task.

Aim: to study health status of children from the families of radiation risk and their parents.

Material and methods: patients aged 1-16 (n=284), born to the contaminated parents with were observed. Their morbidity structure was analysed according to the factors: time period from exposure to child’s birth (from 1 year to 6 and more) (P), parent’s age at the moment of contamination (18-36 and older) (A).

Results: Diseases of endocrine, respiratory, musculoskeletal system, blood, congenital abnormalities, ranked in children more often (1st-5th, 4th-8th, 6th-13th, 2nd-12th corr., p<0.001), than in their parents, in the latter – diseases of nervous, circulatory, digestive and urinary system (1st-5th, 2nd-3rd, 3rd-8th, 4th-9th corr., p<0.001). Number of simultaneously involved into pathologic process systems were 4-9(P1), 6-12(P2), 7-12(P3-4), 8-13(P5), 3-8(P6), 4-10(A18-20, 26-35), 5-13(A20-25) and 2-9 (A36>). (77,8%,90%,92,9%,75%,83,3%,100%, 93,3%, 100% corr.), with affected systems coefficient (ASC) in parent-child pairs in 1.24 times more in children than in their parents (7,38±1,49 against 5,97±0,48 corr. (CI 95%) with strong negative correlation between ASC parents and their children (r=-0.7, p=0.017).

Conclusions: 1. Influence of time factor on health status of children from radiation risk families is determined: in children, born in 3-5 years after their parents’ exposure with their contamination at the age 20-25 years more severe consequences for health status were revealed.

2.System involvement into pathological process is 1.24 more in descendants than in parents with strong negative correlation between ASC parents and their children.