Mortality of diabetic patient with surgical intervention for infective endocarditis

Objective: Type 2 diabetes mellitus (DM) is a frequent co-morbidity among patients undergoing surgical procedures due to infective endocarditis. The aim of the study was to evaluate the impact of type 2 DM on the early- and long-term outcomes of patients who underwent surgical repair due to infective endocarditis. Methods: We performed an observational cohort study in the large tertiary center during 14 years. All data of patients who underwent surgery due to infective endocarditis , performed between 2004 and 2019 were extracted from the departmental database. Patients were divided into two groups: Group I (non-diabetic patients), and Group II (diabetic patients).

Results: The study population includes 420 patients. Group I (non-diabetic patients), comprise 326 patients, and Group II (diabetic patients), comprise 94 patients. Mean follow-up duration was 40±47months. In-hospital mortality was similar between Group I and II (25% vs. 11%, p=0.215). Long term mortality was higher in the DM group compared with the Non DM group(21% vs. 40%, p=0.001). Conclusions: Survival of diabetic patients started deteriorates after more than three year follow surgery. Type 2 DM is an independent predictor for long-term mortality after surgical intervention for infective endocarditis .