The 68th Annual Conference of the Israel Heart Society in association with the Israel Society of Cardiothoracic Surgery

Effect of vacation on the clinical outcomes of patients with ST elevation myocardial infarction

Eed Abu-Zaid 1 Omri Simchon 1 Orit Barrett 1 Ido Peles 2 Ala Abu Dogosh 1 Edward Koifman 1 Doron Zahger 1 Yigal Abramowitz 1
1Cardiology, Soroka University Medical Center, Ben-Gurion University of the Negev, Israel
2Clinical Research Center, Soroka Medical Center, Ben-Gurion University of The Negev, Israel

Background

Vacations, holidays, and traveling were previously found to be associated with increased incidence, and worse clinical outcomes of ST-Elevation myocardial infarction (STEMI). Nonetheless, the data of these previous studies is inconsistent and scarce. We aimed to investigate the clinical outcomes of patients that had STEMI during vacation in Eilat compared to STEMI patients that are Eilat residents.

Methods

A population based retrospective cohort study including all patients who presented to Yoseftal emergency department with clinical STEMI that received thrombolytic therapy and transferred to Soroka Medical Center between the years 2010 and 2020. The Primary endpoint was all-cause mortality at 1-year. Secondary endpoints included in-hospital cardiovascular death, in-hospital non-fatal stroke, post PCI ventricular tachycardia (VT)/ ventricular fibrillation (VF) and discharge left ventricular ejection fraction (LVEF).

Results

A total of 344 STEMI patients were included to the study, of them 105 (30.5%) were vacationers and 239 (69.5%) were Eilat residents. All baseline clinical variables did not differ significantly between the two study groups. STEMI features, including MI`s territory, and the number of diseased vessels were similar between groups. All-cause 1- year mortality was 6 (5.7%) in the vacationers group and 12 (5%) in the residents group (p=0.99). In-hospital cardiovascular death occurred in 2 (1.9%) patients in the vacationers group compared to 3 (1.3%) in the residents group (p=0.27). Rate of in-hospital non-fatal stroke was 2 (1.9%) in the vacationers vs. 2(0.8%) in the residents group, respectively (p=0.066). Rate of post PCI VT/VF was 5.8% in the vacationers and 3.8% in the residents group (p=0.03). Discharge LVEF was similar in both groups.

Conclusions

In this study comparing clinical outcomes of vacationers and residents post STEMI we found a higher incidence rate of post PCI VT/VF in patients that had STEMI during vacation. All other short and mid-term outcomes were similar between both groups.









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