
Background/Rationale:
Anterior knee pain (AKP) affects up to 15% of recruits to elite military units. Its incidence is significantly higher in female combatants. Gender differences in the effect of AKP on functional disability have not been reported.
Methods:
This is a subgroup analysis by gender of data from an interventional study (NCT02845869). Inclusion: active combat soldiers/policemen with AKP due to overuse/load. Exclusions: previous trauma, knee surgery, or injury to meniscus/ligament. Outcomes: anatomical pain location, subjective pain level by visual analogue scale (VAS [0=no pain, 100=unbearable pain), and Kujala AKP functional disability questionnaire (0=worst, 100=best). Kujala questions were dichotomized by significance to combat soldiers, and the proportion of the population affected was determined for each. Comparisons of males/females were performed with 2-sample t-test or χ2.
Results:
AKP on the background of overuse/load was diagnosed in 45 men and 27 women (71 and 41 knees, respectively). Female combatants were younger (20.1±1.3-vs-22.9±6.3 years, p<0.001), had lower BMI (23.0±3.2-vs-24.6±3.2 kg/m, p=0.006), and reported doing less pre-induction physical training (67%-vs-89%, p=0.021). Location of pain was similar between male and female soldiers (female-vs-male: patella, 32%-vs-48%, p=0.095; patellar tendon, 59%-vs-51%, p=0.423). Female combatants reported significantly higher subjective pain levels (VAS: 53.5±22.6-vs-44.5±22.9, p=0.046) and decreased overall functionality (Kujala: 67±12-vs-73±11, p=0.030). When analyzed by specific activity, female soldiers had higher frequency of further detrimental effect of AKP when climbing stairs and while running (female-vs-male: stairs, 82%-vs-56%; running, 30%-vs-9%, p=0.025 and p=0.022, respectively).
Conclusions:
Compared to their male counterparts, female combatants with AKP report higher pain levels and greater overall functional disability with significantly more difficulties when climbing/descending stairs or running. This study emphasizes the need for a gender-specific approach to diagnosis and treatment of AKP to achieve optimal outcome and earlier return to service.