Mechanisms for root meristem shaping

Growth extent and direction determine cell and whole-organ architecture. How they are spatio-temporally coordinated across distinct cell types is one of the questions tackled in our lab. Using a variety of approaches ranging from developmental genetics to precise tools that quantify single-cell growth parameters in 4D, we study the role of hormonal signaling, tissue identity and mechanical constraints that together dictate the developmental output. We focus on the Arabidopsis root as a model organ and on the critical brassinosteroid signaling pathway, as an entry point to elucidate developmental processes. This talk will highlight the use of quantitative approach and modeling towards revealing the control of growth directionality at both the cell and meristem levels and the coordination between tissue layers that shape the meristem.