Cellulose is the primary constituent of biomass and the most important potential source of biofuel. However degradation of cellulose requires harsch conditions that are poorly compatible with synthesis of sensitive compounds. For example synthesis of furanics from cellulose is typically accompanied by extensive humin formation and subsequent low yields. In this presentation efforts to improve the conversion of cellulose into volatile organic compounds, using either new reactions and conformationally activated cellulose, will be described.