Neurosporaside, which was isolated from the fungus Neurospora crassa, bears a sugar chain unprecedented among natural glycoconjugates[1]. The fungal glycosphingolipids may serve as key ligands for some endogenous lectins in animals. However, the Neurosporaside is present in N. crassa in lesser. In order to elucidate the comprehension of lipid structural biology, here we report the concise chemical synthesis of Neurosporaside.
References
[1] Valeria Costantino, Alfonao Mangoni, Roberta Teta, Galia Kra-Oz, and Oded Yarden. J. Nat. Prod. 2011, 74, 554–558.
