Our group has recently developed a fluorescent molecular sensor that mimics the function of optical cross-reactive sensor arrays (the so-called chemical "noses"/"tongues").1The molecule-sized diagnostic system, which combines several recognition elements and four fluorescence-emission channels, can identify a wide range of saccharides, including various carbohydrate-based drugs associated with counterfeiting or medication errors. This talk will highlight the principles of operating this system and will show how it could be used to analyze drug concentrations and combinations in human urine, in a high-throughput manner.
1) Rout, B., Unger, L., Armony, G., Iron, M. A., Margulies, D. Angew. Chem. Int. Ed. 2012,51, 12477-12481.
