Combined Transcatheter Aortic Valve Impantation (TAVI) and Stenting of the Coronary Arteries in Patients
with Severe Aortic Stenosis

David Iosseliani Haim Danenberg Anton Koledinsky Igor Arabadzhyan Elena Kovaleva Vladislav Kriukov Anna Rogatova
Interventional Cardiology, Moscow City Center of Interv. Cardioangiology, Moscow

Purpose: To study the effectiveness and safety of combined PCI and aortic valve implantation in patients at high surgical risk.  

Material and Methods: combined correction of aortic stenosis and  PCI was performed in 15 patients.   The average age of patients was 76,3 ±4,7 years. All patients had severe aortic stenosis and were in NYHA class III-IV. At baseline EchoCG, the average systolic pressure gradient across the aortic valve was 80,1 ±24,9 mm Hg, maximal gradient 117,5 ± 24,4 mm Hg, the area of AV orifice - 0,6 ± 0,27 mm². Surgical risk, as assessed by EuroScore was > 25%, by STS > 15%. Four patients has single-vessel disease, 10 – two-vessel, 1-three-vessel disease. SYNTAX score was 12,4 ± 5,2. Average number of stents per patient was 1.8.

Results: Combined TAVI (CoreValve System)  and PCI were successfully performed in all  patients, without death or intra- and postoperative complications. The average duration of the procedure was 126,3 ± 32,4 min, the time of scopy 35,2 ± 14,27 min. The average volume of the contrast medium was 258,3±22,5 ml.   According to EchoCG, after the procedure maximal systolic pressure gradient of the aortic valve was 18,6 ±6 mm Hg, in 30 days – 17,3 ± 0,6 mm Hg. The duration of hospital stay did not exceed 8 days. At day 30, none of the patients had angina pain, the signs of heart failure were absent.

Conclusions: Transcatheter aortic valve implantation combined with percutaneous coronary interventions can be successfully used for the management of patients at extremely high risk for open-heart surgery and is the only method of treatment for them.









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