Purpose: Acoustic radiation force impulse( ARFI) elastometry is a noninvasive technique for the quantification of tissue stiffnes. The aim of the study was to assess the possibility of applying Acoustic Radiation Force Impulse (ARFI) elastography to detect the pathological changes in parenchymal organs of the abdominal cavity
in children.
Methods: The study examined 120 subjects, aged from 1 month to 18 years old: 84(70%) «normal» subjects without clinical signs and history of disease of abdominal organs, with normal laboratory tests and ultrasonography; 28 (23%) - patients without clinical and laboratory signs, with transient ultrasonography of the parenchymal changes; 8 (7%) - with permanent signs of the parenchyma. All children were examined at the study of abdominal organs that was performed on Siemens Acuson S2000 using conventional ultrasound and ARFI technology. Five valid ARFI measurements (at the same depth and in the same anatomic segments) were conducted in the parenchyma of
each organ.
Results: In our study mean ARFI values for «normal» subjects were obtained:1,3±0,24 m\s- for liver,1,0 ±0,21 m/s -for pancreas, 2,27±0,46 m/s - for spleen. Statistically significant differences by age and sex were not discovered. In the presence of permanent signs the mean ARFI values were various, depending on nosology and differed significantly from the mean ARFI values obtained from the «normal» subjects. In the presence of reactive changes in parenchymal organs the mean ARFI values did not have statistically significant differences from the «normal»
subjects.
Conclusion: The application of ARFI in an integrated ultrasonic diagnosis of abdominal parenchymatous organs pathology in children helps to identify initial diffuse signs of parenchyma and to assess their severity.