Bioaugmentation treatment approach presents both an economical and environmental friendly solution for wastewater treatment. However, the use of exogenous bacterial culture presents several limitations: negative interaction between microorganisms, and adaptation to new physical and chemical composite environment. These selective forces create a significant challenge for the new introduced culture to achieve the required biomass in order to conduct the target biological treatment. The Small-Bioreactor Platform (SBP) technology is aimed to introduce exogenous bacterial culture with some protection and reduce some of the natural selection process. The current study was aimed to validate the use of the SBP technology to improve biological treatment, especially during a stress period, by using macro-encapsulated bio-augmentation treatment. The study results indicated that the use of the SBP technology elevate the stability of the biological treatment, improving operational factors such as the reduction of foaming phenomena, and the reduction of sludge accumulation. Still, a significant study needs to be conducted to understand the potential of this technology; especially, the impact on the biological treatment by using different types of microorganisms for different types of wastewaters and the relationship between the biomass within the SBP capsules and the natural fauna.