Background: Pneumococcal serotypes 1, 5, 7F, 14 and 19A were previously associated with bacteremic pneumonia and empyema and thus titled "pneumonia" serotypes (PnSTs; Greenberg PIDJ 2011). We attempted to assess whether children with Alveolar community acquired pneumonia (A-CAP) colonized with PnSTs differ in their clinical and laboratory characteristics from those not colonized with PnSTs.
Methods: Pneumococcal nasopharyngeal (NP) cultures results and selected clinical and laboratory data were prospectively obtained from children
Results: A total of 1,423 episodes were studied: 300 PnSTs, 591 non-PnSTs. and 532 Pn-negative. ORs (and 95% CI) for children with PnSTs were significantly different from those with non-PnSTs and Pn-negative for the following findings: Temperature ≥ 390C , CRP ≥70.0 µg/L, O2 saturation <95% , Blood sodium
Conclusions: A-CAP episodes in children
