Background: Abnormal renal function is associated with worst outcome in patients with acute ST elevation myocardial infarction (STEMI). Estimated creatinine clearance (eCCT) or glomerular filtration rate (eGFR) are used to assess renal function before primary percutaneous coronary intervention (PPCI).
Aim: Evaluate the effect of renal function at admission in acute anterior STEMI and PPCI on coronary and myocardial flow and left ventricular systolic function.
Methods: One hundred thirty four patients with anterior STEMI treated by PPCI were studied. TIMI and myocardial blush (MBG) grades before and after PPCI and ST elevation resolution were assessed. Left anterior descending coronary artery (LAD) flow parameters, left ventricular ejection fraction (LVEF), wall motion score index (WMSI) and LAD-WMSI were evaluated early after PPCI and before discharge.
Results: Patients with STEMI and normal renal function were younger, with higher frequency of men and smoking. TIMI grades and MBG before and after PPCI were similar between the groups. Absence of ST elevation resolution was more frequent in those with eCCT or eGFR between 30 and 60ml/min 42.8%, vs. 5% in those with normal renal function, p valueConclusions: Mild and moderate renal dysfunction did not affect PPCI outcome or LV systolic function in patients with anterior STEMI undergoing PPCI.
